Three Powerful Tailwinds

Minimally Invasive Trend

Endovascular procedures have grown exponentially as the field continues to push toward minimally invasive treatment options for vascular disease.

Cross-Specialty Demand

Multiple specialties perform endovascular procedures: vascular surgery, cardiology, interventional radiology, and other interventional subspecialties.

Multi-Procedure Application

Applicable across peripheral arterial disease, deep vein thrombosis, and dialysis access — each a large and growing market segment.

Global Market Estimates Over $20B

The Upstream Access system addresses three major clinical applications across a massive global market in endovascular procedures.

Peripheral Arterial Disease $201M

412,000 revascularizations/year

Hemodialysis Access $391M

800,000 patients via catheter/year

Deep Vein Thrombosis $39M

80,000 mechanical thrombectomies/year

Global Market Opportunity

Over $20B

Global market estimates across peripheral arterial disease, hemodialysis access, and deep vein thrombosis procedures.

Three Major Procedure Categories

Peripheral Arterial Disease

250K+
Procedures per year

$10,000-$25,000 per intervention. Growing incidence with aging population and diabetes prevalence.

Dialysis Access

350K+
Procedures per year

$1,800-$5,200 per intervention. ~60% of AV fistulas fail within year 1, requiring repeat procedures.

Deep Vein Thrombosis

900K
Patients per year

~8.8% receive mechanical thrombectomy. Growing adoption of minimally invasive techniques.

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